Incidence and management practices of bacterial meningitis in children in Morogoro regional referral hospital

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dc.contributor.authorChambuso, Ramadhani
dc.date.accessioned2025-09-24T12:35:04Z
dc.date.available2025-09-24T12:35:04Z
dc.date.issued2013
dc.descriptionMaster's Theses
dc.description.abstractThe analysis and evaluation of meningitis situation in Morogoro Region was done by looking at the incidence and management practices of meningitis in children at the Morogoro Regional Referral Hospital (MRRF) for a period of 7 months. A total of 1352 children aged between 7 days and 12 years were admitted at MRRH, of these 72 (5.3%) had meningitis symptoms during the period. Lumbar puncture was done on the 72 children with meningitis symptoms to collect CSF for observation and laboratory analysis. Of the examined CSF samples, 23 (31.9%) were positive for Streptococcus pneumoniae, 6 (8.3%) for Haemophilus influenzae, 5 (6.9%) for Group B Streptococcus, 3 (4.2 %) for Echerichia coli and one (1.4%) was AFB positive on Ziehl-Neelsen (ZN) stain. Thirty nine percent (n=72) of the samples showed no bacterial growth in the culture media. Latex agglutination test was used to confirm the bacterial colonies. The incidence of meningitis infection was 5.3% (n=1352) among the admitted patients. Intravenous administration of Ceftriaxone at 80mg/kg body weight was given once a day for 10 days to all the 72 children with symptoms of meningitis. Of the 72 treated children, 32 (44.4%) responded well to the treatment of whom 19 (26.4%) fully recovered, while 13 (18.1%) recovered but with neurological defects. Nevertheless, 39 (54.2%) of the treated children did not respond to the therapy whereas 31 (43.1%) of them died while 8 (11.1%) were referred to the Muhimbili National Referral Hospital. Only one case of Tuberculosis (TB) Meningitis was recorded which responded well to TB medication of rifampicin, isoniazid and pyrazinamide in a combination. This study has shown that Streptococcus pneumoniae was the major bacteria associated with meningitis in children admitted at the MRRH.
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/7049
dc.language.isoen
dc.publisherSokoine University of Agriculture
dc.subjectIncidence
dc.subjectmanagement practices
dc.subjectbacterial meningitis- children
dc.subjectMorogoro regional referral hospital
dc.titleIncidence and management practices of bacterial meningitis in children in Morogoro regional referral hospital
dc.typeThesis

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