Effect of Hormonal baits (Levonorgestrel and Quinestrol) on Fertility of Commensal Rat (Rattus rattus linnaeus, 1758)

Simple item page
dc.contributor.authorSelemani, Mwajabu
dc.date.accessioned2021-10-04T08:28:55Z
dc.date.available2021-10-04T08:28:55Z
dc.date.issued2021
dc.descriptionDissertationen_US
dc.description.abstractThis laboratory-based study examined the effects of quinestrol and levonorgestrel (singly and in combination) incorporated in bait on body mass and reproduction of the roof rat (Rattus rattus ). A total of 140 R. rattus, (70 males and 70 females) were provided with 10 g of bait containing quinestrol (QU) or levonorgestrel (LE) or a combination of levonorgestrel and quinestrol (EP-1) at concentrations of (10 ppm and 50 ppm) for seven consecutive days consecutively. After 7 days, animals were dissected and the ovary, uterus, testis, seminal vesicles, and epididymis were weighed and examined. Bait consumption and body weight decreased significantly (p = 0.0001) in treated compared to control animals, with a minor difference between sexes. Quinestrol and EP-1 at 10 ppm and 50 ppm increased the mass of the uterus and ovary of females (p = 0.0001), which was associated with edema in the uterus. The mass of epididymis, testis, seminal vesicles, were reduced and sperm counts and motility were significantly reduced (p = 0.0001) particularly in the animals with QU and EP-1 at the higher concentrations. To determine the effects of contraceptive hormones on reproduction, 50 ppm of QU and EP-1 were used. A total of 160 animals of equal numbers and sexes were paired, keeping the ratio of one female to one male. Pregnancy and litter production was significantly reduced (p = 0.0249) in the treated pairs when compared to controls. It is concluded that quinestrol and EP-1 have a significant impact on both males and females R. rattus reproduction compared to levonorgestrel alone. These hormones will be very valuable when used as a fundamental method in controlling R. rattu reproduction.en_US
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/3872
dc.language.isoenen_US
dc.publisherSokoine University of Agricultureen_US
dc.subjectHormonal baitsen_US
dc.subjectLevonorgestrel and Quinestrolen_US
dc.subjectFertilityen_US
dc.subjectCommensal Raten_US
dc.subjectRattus rattus linnaeusen_US
dc.titleEffect of Hormonal baits (Levonorgestrel and Quinestrol) on Fertility of Commensal Rat (Rattus rattus linnaeus, 1758)en_US
dc.typeThesisen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
mwajabu dissertation HB 26.10.2020.edited.pdf
Size:
813.74 KB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.67 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Theses and Dissertations Collection