Molecular epidemiology of rift valley fever and its socio-economic impact in selected areas of Tanzania
| dc.contributor.author | CHENGULA,AUGUSTINO ALFRED | |
| dc.date.accessioned | 2025-03-04T08:01:13Z | |
| dc.date.available | 2025-03-04T08:01:13Z | |
| dc.date.issued | 2013 | |
| dc.description | Thesis | |
| dc.description.abstract | Rift Valley fever (RVF) is a viral notifiable zoonotic disease primarily of domestic ruminants that cause significant socio-economic impacts. Using the 2006-07 outbreak cases, this study aimed to establish the molecular epidemiology of Rift Valley fever virus (RVFV) and its socio-economic impact in selected areas of Tanzania. Data for awareness and socio-economic study were collected in Arusha, Manyara and Morogoro regions using questionnaires, focus group discussions and in-depth interviews with key informants. Molecular epidemiological study used samples that were collected during the outbreaks. Analysis of selected samples was done using RVF Inhibition Enzyme-Linked Immunosorbent Assay (ELISA) and Reverse Transcription Polymerase Chain Reaction (RT-PCR). Results indicate that there was little knowledge on disease (all clinical signs scored <50%) and the difference between the three regions was statistically significant (P=0.00459). Socio-economic impacts of RVF shown by this study included; animal and human deaths, disruption of livestock market chains, inability of pastoralists to achieve their daily demands, inability to obtain protein leading to malnutrition and monetary loss at individual and national level during control of the disease. The proportion of positive serum samples by RVF inhibition ELISA was 39.5% (n=200) and 17.6% (n-108) by RT-PCR. ELISA detected 41 (38.7%). 32 (39.0%) and 6 (50.0%), the RT-PCR detected II (0.2%). 7 (0.2%) and 1 (0.1%) positive results in cattle, goats and sheep respectively. These findings have demonstrated low knowledge of community on RVF and the presence of RVF virus in the country. Thus, more education and engagement is needed to the community together with further characterization of the virus from different geographical locations in order toiii establish the profile of strains circulating in the country and develop more effective and efficient control strategies. | |
| dc.identifier.uri | https://www.suaire.sua.ac.tz/handle/123456789/6602 | |
| dc.language.iso | en | |
| dc.publisher | Sokoine University of Agriculture | |
| dc.subject | Molecular epidemiology | |
| dc.subject | rift valley fever | |
| dc.subject | socio-economic impact | |
| dc.subject | Zoonotic disease | |
| dc.title | Molecular epidemiology of rift valley fever and its socio-economic impact in selected areas of Tanzania | |
| dc.type | Thesis |