Articles, Conference and Workshop Papers Collection

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Browsing Articles, Conference and Workshop Papers Collection by Subject "Aflatoxin"

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    Assessment of knowledge, attitude, and practices of maize farmers following post-intervention programs to mitigate aflatoxin contamination in Chamwino, Dodoma, Tanzania
    (Urmia University, 2025) Msangi, Riziki Salehe; Issa-Zacharia, Abdulsudi; Chove, Lucy Mlipano
    Aflatoxin contamination poses a significant threat to agricultural systems and public health, particularly in regions such as Dodoma, where favorable climatic conditions promote the growth of aflatoxin-producing fungi. Various interventions were initiated to address the problem of aflatoxin contamination among maize farmers in Dodoma. This study aimed to assess maize farmers' knowledge, attitudes, and practices (KAP) following intervention programs designed to mitigate aflatoxin contamination in Chamwino district, Dodoma. A cross-sectional survey was conducted in five wards of Chamwino District: Chilonwa, Msanga, Chamwino, Majeleko, and Buigiri. A semi-structured questionnaire was administered to 300 maize farmers to assess their KAP related to aflatoxin contamination. Data were analyzed using SPSS version 26, with significance set at p ≤ 0.05. Among 300 farmers surveyed, 221 (73.7%) demonstrated awareness of aflatoxin-related interventions, whereas 79 (26.3%) did not exhibit such awareness. Of the 221 informed farmers, 123 (55.7%) demonstrated good knowledge, 51 (23.1%) exhibited medium knowledge, and 47 (21.3%) displayed poor knowledge regarding aflatoxin contamination and its mitigation. Of the participants, 186 (84.2%) exhibited positive attitudes, 34 (15.4%) displayed medium attitudes, and only 1 (0.5%) demonstrated poor attitudes. Of the participants, 157 (71.0%) exhibited good practices, while 64 (29.0%) were categorized as having medium-level practices. No farmers demonstrated poor practices regarding aflatoxin contamination and mitigation. The interventions effectively enhanced awareness, knowledge, attitudes, and practices regarding aflatoxin mitigation among maize farmers in Chamwino District. Future interventions should strengthen collaboration between government agencies, Non-Government Organizations, farmer groups, and local communities to sustain and expand these gains.
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    A Prospective Study of Growth and Biomarkers of Exposure to Aflatoxin and Fumonisin during Early Childhood in Tanzania
    (BMC [Commercial Publisher], 2015-10) Shirima, Candida P.; Kimanya, Martin E.; Routledge, Michael N.; Srey, Chou; Kinabo, Joyce L.; Hans‐Ulrich Humpf, Hans‐Ulrich; Wild, Christopher P.; Tu, Yu-Kang; Gong, Yun Yun
    Background: Aflatoxin and fumonisin are toxic food contaminants. Knowledge about effects of their exposure and coexposure on child growth is inadequate. Objective: We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. Methods: A total of 166 children were recruited at 6–14 months of age and studied at recruitment, and at the 6th and 12th month following recruitment. Blood and urine samples were collected and analyzed for plasma aflatoxin–albumin adducts (AF-alb) using ELISA, and urinary fumonisin B1 (UFB1) using liquid chromatography–mass spectrometry, respectively. Anthropometric measurements were taken, and growth index z-scores were computed. Results: AF-alb geometric mean concentrations (95% CIs) were 4.7 (3.9, 5.6), 12.9 (9.9, 16.7), and 23.5 (19.9, 27.7) pg/mg albumin at recruitment, 6 months, and 12 months from recruitment, respectively. At these respective sampling times, geometric mean UFB1 concentrations (95% CI) were 313.9 (257.4, 382.9), 167.3 (135.4, 206.7), and 569.5 (464.5, 698.2) pg/mL urine, and the prevalence of stunted children was 44%, 55%, and 56%, respectively. UFB1 concentrations at recruitment were negatively associated with length-for-age z-scores (LAZ) at 6 months (p = 0.016) and at 12 months from recruitment (p = 0.014). The mean UFB1 of the three sampling times (at recruitment and at 6 and 12 months from recruitment) in each child was negatively associated with LAZ (p < 0.001) and length velocity (p = 0.004) at 12 months from recruitment. The negative association between AF-alb and child growth did not reach statistical significance. Conclusions: Exposure to fumonisin alone or coexposure with aflatoxins may contribute to child growth impairment. Citation: Shirima CP, Kimanya ME, Routledge MN, Srey C, Kinabo JL, Humpf HU, Wild CP, Tu YK, Gong YY. 2015. A prospective study of growth and biomarkers of exposure to aflatoxin and fumonisin during early childhood in Tanzania. Environ Health Perspect 123:173–178;  http://dx.doi.org/10.1289/ehp.1408097