Evaluation of chemotherapeutic and prophylactic efficacy of Kelamedium® in Bovine trypanosomosis

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dc.contributor.authorNonga, H.E.
dc.contributor.authorKambarage, D.M.
dc.date.accessioned2018-04-19T09:33:53Z
dc.date.available2018-04-19T09:33:53Z
dc.date.issued2008-12-20
dc.description.abstractChemotherapeutic and chemo-prophylactic efficacy of Kelamedium® an isometamidium was evaluated in five medium dairy farms and two traditional herds with a number of animals above 6 months age being 275 and 100 respectively. The trial also involved 42 smallholder dairy herds with 316 animals. The animals were clinically examined for trypanosomosis signs then screened for haemoparasites using blood smears and micro-centrifugation methods. Positive animals on smears were classified as “cases” and were treated with a curative dose (1 mg/kg bodyweight) of Kelamidium® and monitored for parasitological recovery on days three, six and nine. A total of six “cases” were encountered and five which were treated with Kelamidium® showed parasitogical and clinical recovery by days 3 and 9 respectively, whereas one animal died. Smear negative animals were randomly assigned to two treatment groups; with one group receiving a prophylactic dose (0.5 mg/kg) of Kelamidium® and the controls being treated with the same dose of Samorin®. These animals were then monitored clinically and re-screened on days 60 and 90-post intervention for re-infections. Kelamidium® showed a prophylactic efficacy of 99.4% and this was comparable (p>0.05) to that of Samorin® (99.7%). These results thus show that Kelamidium® offers an alternative choice to Samorin®.en_US
dc.description.sponsorshipKela (Hoogstraten Laboratories Belgium)en_US
dc.identifier.issn0378-9721
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/2091
dc.language.isoenen_US
dc.publisherAFRICAN UNIONen_US
dc.subjectTrypanosomosisen_US
dc.subjectKelamediumen_US
dc.subjectCattleen_US
dc.subjectHaemoparasites chemotherapeuticen_US
dc.subjectChemo-prophylactic*en_US
dc.titleEvaluation of chemotherapeutic and prophylactic efficacy of Kelamedium® in Bovine trypanosomosisen_US
dc.typeArticleen_US
dc.urlhttps://www.ajol.info/index.php/bahpa/article/view/43298en_US

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