"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses

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dc.contributor.authorGryseels, Sophie
dc.contributor.authorRieger, Toni
dc.contributor.authorOestereich, Lisa
dc.contributor.authorCuypers, Bart
dc.contributor.authorBorremans, Benny
dc.contributor.authorMakundi, Rhodes
dc.contributor.authorLeirs, Herwig
dc.contributor.authorGünther, Stephan
dc.contributor.authorGoüy de Bellocq, Joëlle
dc.date.accessioned2016-12-06T06:27:37Z
dc.date.available2016-12-06T06:27:37Z
dc.date.issued2015
dc.description.abstractDespite itsnearpan-Africanrange,theNatalmultimammatemouse, Mastomysnatalensis, carriesthe human pathogenLassavirusonlyinWestAfrica,whiletheseeminglynon-pathogenicarenaviruses Mopeia, Morogoro,andLunahavebeendetectedinthissemi-commensalrodentinMozambique/ Zimbabwe,TanzaniaandZambia,respectively.Here,wedescribeanovelarenavirusin M. natalensis from Gairo districtofcentralTanzania,forwhichweproposethename “Gairo virus”. Surprisingly,thevirusis not closelyrelatedwithMorogorovirusthatinfects M. natalensis only 90kmsouthofGairo,butclusters phylogeneticallywithMobala-likevirusesthatinfectnon-M. natalensis host speciesinCentralAfrican RepublicandEthiopia.Despitetheevolutionarydistance,Gairovirussharesbasicecologicalfeatures with theother M. natalensis-borne virusesLassaandMorogoro.Ourdatashowthat M. natalensis, carrying distantlyrelatedviruseseveninthesamegeographicalarea,isapotentreservoirhostfora varietyofarenaviruses.en_US
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/1085
dc.language.isoenen_US
dc.publisherElsevierIncen_US
dc.subjectArenavirusen_US
dc.subjectMastomys natalensisen_US
dc.subjectVirologyen_US
dc.subjectPhylogenyen_US
dc.subjectEcologyen_US
dc.subjectZoonotic infectionsen_US
dc.subjectHemorrhagic feversen_US
dc.subjectTanzaniaen_US
dc.title"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro virusesen_US
dc.typeArticleen_US
dc.urlwww.elsevier.com/locate/yviroen_US

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