Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.

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dc.contributor.authorChuma, I. S
dc.contributor.authorBatamuzi, E. K.
dc.contributor.authorCollins, D. A.
dc.contributor.authorFyumagwa, R. D.
dc.contributor.authorHallmaier-Wacker, L. K.
dc.contributor.authorKazwala, R. R.
dc.contributor.authorKeyyu, J. D.
dc.contributor.authorLejora, I. A.
dc.contributor.authorLipende, I. F.
dc.contributor.authorLüert, S.
dc.contributor.authorPaciência, F. M.D.
dc.contributor.authorPiel, A.
dc.contributor.authorStewart, F. A.
dc.contributor.authorZinner, D.
dc.contributor.authorRoos, C.
dc.contributor.authorKnau, S.
dc.date.accessioned2018-06-14T06:41:57Z
dc.date.available2018-06-14T06:41:57Z
dc.date.issued2018
dc.descriptionEmerging Infectious Disease .Vol. 24, No. 6—June 2018en_US
dc.description.abstractWe investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015–2017. We used a serologic treponemal test to detect antibodies against the bacterium. Infection was further confirmed from tissue samples of skin-ulcerated animals by 3 independent PCRs (polA, tp47, and TP_0619). Our findings indicate that T. pallidum infection is geographically widespread in Tanzania and occurs in several species (olive baboons, yellow baboons, vervet monkeys, and blue monkeys). We found the bacterium at 11 of 14 investigated geographic locations. Anogenital ulceration was the most common clinical manifestation; orofacial lesions also were observed. Molecular data show that nonhuman primates in Tanzania are most likely infected with T. pallidum subsp. pertenue–like strains, which could have implications for human yaws eradication.en_US
dc.identifier.issn1080-6040
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/2357
dc.language.isoenen_US
dc.publishercenters for disease control and prevention.en_US
dc.subjectTreponema.en_US
dc.subjectInfection.en_US
dc.subjectPrimates.en_US
dc.subjectTanzania.en_US
dc.subjectSpecies.en_US
dc.subjectPallidum infection.en_US
dc.titleWidespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.en_US
dc.typeArticleen_US
dc.url: https://doi.org/10.3201/eid2406.180037en_US

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