Browsing by Author "Massawe, Apia W"

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Does exploratory behavior or activity in a wild mouse explain susceptibility to virus infection?
(Oxford university press., 2017-09) Makundi, Rhodes H.; Massawe, Apia W; Leirs, Herwig; Hughes, Nelika K; Broecke, Bram V; Borremans, Benny; Mariën, Joachim
Exploration and activity are often described as trade-offs between the fitness benefits of gathering information and resources, and the potential costs of increasing exposure to predators and para- sites. More exploratory individuals are predicted to have higher rates of parasitism, but this relationship has rarely been examined for virus infections in wild populations. Here, we used the multimammate mouse Mastomys natalensis to investigate the relationship between exploration, activity, and infection with Morogoro virus (MORV). We characterized individual exploratory behav- ior (open field and novel object tests) and activity (trap diversity), and quantified the relationship between these traits and infection status using linear regression. We found that M. natalensis expresses consistent individual differences, or personality types, in exploratory behavior (repeat- ability of 0.30, 95% CI: 0.21–0.36). In addition, we found a significant contrasting effect of age on ex- ploration and activity where juveniles display higher exploration levels than adults, but lower field- activity. There was however no statistical evidence for a behavioral syndrome between these 2 traits. Contrary to our expectations, we found no correlation between MORV infection status and exploratory behavior or activity, which suggests that these behaviors may not increase exposure probability to MORV infection. This would further imply that variation in viral infection between individuals is not affected by between-individual variation in exploration and activity.
Relationships between seasonal changes in diet of Multimammate rat (Mastomys natalensis) and its breeding patterns in semi-arid areas in Tanzania
(Cogent food and agriculture, 2018-09) Makundi, Rhodes H; Isabirye, Moses; Kifumba, David; Mdangi, Mashaka E; Nakiyemba, Alice; Leirs, Herwig; Belmain, Steven R; Mulungu, Loth S; Massawe, Apia W; Tarimo, , Akwilin J. P; Kimaro, Didas N; Mariën, Joachim; Mlyashimbi, Emmanuel C. M
The diet and breeding patterns of Mastomys natalensis in semi-arid areas of Isimani division, Iringa region, Tanzania were investigated in maize fields and fallow land. The aim was to investigate the influence of diet on breeding patterns of M. natalensis. Removal trapping was used to capture rodents and analyse diet categories while Capture-mark-release trapping was used to investigate breeding patterns of female M. natalensis. Mastomys natalensis comprised 94% of the total capture, and the remaining 6% comprised of six other species. Statistical analysis of food preferences indicated that both vegetative materials and seeds were significantly higher in the overall diet of M. natalensis compared with other food materials. Significant differences in the proportions of vegetative materials and seeds were found between seasons (dry, wet), but not between habitats (fallow, maize). There was a clear seasonal pattern in the proportion of reproductively active females with peaks in April and troughs in October. The proportion of vegetative materials was highest during the wet season and correlated positively with reproductive activity, suggesting that vegetative materials contain certain compounds (e.g. 6-MBOA) that trigger reproductive activity in M. natalensis. The breeding activity of M. natalensis in semi-arid areas might, thus, be reduced by limiting access to fresh vegetative food (e.g. young sprouting grass).
Serological survey of leptospira spp. in livestock and rodents from different settlements in the kilombero wetland, Tanzania
(Pathogens, 2024-11-25) Selemani, Mwajabu; Makundi, Rhodes H; Massawe, Apia W; Katakweba, Abdul S
Background: The circulation of Leptospira has been linked to various occupational activities globally. This study investigated the seroprevalence of Leptospira spp. in rodents and livestock (cattle and goats) in three settlements/villages involved in agriculture, livestock keeping, and mixed agriculture and livestock in the Kilombero district, Tanzania. Methods: Data were collected dur- ing the wet and dry seasons. A total of 179 rodents were live-captured from selected habitats. Livestock samples were collected from 80 cattle in a livestock settlement and 120 goats from both livestock and mixed agricultural–livestock settlements. The microscopic agglutination test was utilized to identify Leptospira serovars. Results: The seroprevalence of Leptospira spp. was 17.3% in rodents (21.7% in Mastomys natalensis and 3.9% in Rattus rattus) and 8.3% in livestock (13.5% in cattle and 12.6% in goats). The prevalence among rodents and livestock differed between settlements (p = 0.01). A higher prevalence was observed among rodents in the agricultural settlement relative to the other settlements. A higher prevalence of antibodies in livestock was observed in the live- stock settlement compared with the mixed agricultural–livestock settlement. The Leptospira serovars Sokoine (serogroup Icterohaemorrhagiae) and Hebdomadis (serogroup Hebdomadis) were detected in both rodents and livestock. The serovars Hardjo (serogroup Sejroe) and Gripothyphosa (serogroup Gripothyphosa) were found exclusively in cattle, whereas the serovars Pomona (serogroup Pomona) and Lora (serogroup Australis) were identified in rodents. Leptospira antibodies were found to be elevated during the rainy season compared with the dry season (p = 0.05) in all settlements, with the exception of rodents in the mixed agricultural–livestock settlement. Conclusions: This study demon- strates the presence of anti-Leptospira antibodies in rodents and livestock related to occupational activities in human settlements. It further demonstrates that wild animals (rodents) and livestock are reservoirs of Leptospira and are important in the epidemiology of leptospirosis. Management and control strategies should target both rodents and livestock.