Browsing by Author "Gwimo, Nancy"

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    Epidemiological investigation of multi-drug resistant staphylococcus aureus from patients and environment at Morogoro referral regional hospital, Tanzania
    (Sokoine University of Agriculture, 2021) Gwimo, Nancy
    The MDR S. aureus is a significant nosocomial pathogen and has been associated with significant morbidity and mortality in the world. In hospital settings, pathogens, such as multidrug resistance (MDR) Staphylococcus aureus can be transmitted via health care workers (HCWs), patients, and visitors resulting in hospital-associated infections that are difficult to treat. This was a cross-sectional study, comparing carriage and pattern of drug resistant S. aureus between patients and equipment in the hospital. The study involved sampling of patients and environment at MRRH. It undertook the following: isolation of S. aureus, gram staining, catalase test (slide test), coagulase test, antibiotic susceptibility of isolated S. aureus, D Test, MRSA detection and questionnaire survey. An assessment was done on the distribution of Staphylococcus aureus based on age and gender and the risk factors associated with Staphylococcus aureus in the hospital. Also, antibiotic susceptibility test of isolated Staphylococcus aureus was done and from the questionnaire survey, assessment of awareness and perception among patients at the Morogoro Regional Referral Hospital (MRRH) was done. Results of this research highlighted the burden and pattern of Antimicrobial Resistance (AMR) at the hospital and can be used as a model to further collect data in Tanzania on MRSA and essentially provide an insight into the magnitude of the problem. A higher prevalence of MRSA was observed in patients compared to the environment around the hospital, making it significantly different.