Jesse, Angela Mcharo2026-04-282026-04-282026https://doi.org/10.37284/eajis.9.1.48482707-529Xhttps://www.suaire.sua.ac.tz/handle/20.500.14820/7505Original ArticleEmploying a convergent parallel research design and the social ecological model, the study investigated students’ awareness of Hepatitis B and the vaccine at Sokoine University of Agriculture. This is due to the high prevalence of the mentioned disease despite different efforts to contain it under the World Health Organization and health ministries of different countries, including Tanzania. A sample of 168 finalist students aged from 21 to 30 situated at the university hostels and the key informants from the SUA Health Department were involved in the study. A desk review method was used to collect data of the same from different studies conducted at higher learning institutions. The study found that 68.30% of the students were not aware of hepatitis B in terms of its transmission, prevention and cure. The study also found that most of the respondents had little understanding of the Hepatitis B vaccine in terms of dosage per person’s age. Moreover, results from the desk review revealed that students from health institutions were also lacking knowledge on Hepatitis B, while some had the notion that providing the vaccine was among the ways of accelerating unsafe sexual activities. The study concludes that knowledge on Hepatitis B and vaccination compliance at higher learning institutions is minimal despite the huge interaction, which could facilitate learning as stipulated in the social ecological model. It is recommended that health departments within institutions should introduce awareness campaigns and other applicable strategies to raise awareness on health issues, including Hepatitis B and other communicable and non-communicable diseases.enSocial Ecological ModelHepatitis BAwarenessHepatitis B vaccineStudents’ responsivenessArticle