Sokoine University of Agriculture

First Report on a Randomized Investigation of Antimicrobial Resistance in Fecal Indicator Bacteria from Livestock, Poultry, and Humans in Tanzania

Show simple item record

dc.contributor.author Katakweba, Abdul A. S.
dc.contributor.author Muhairwa, Amandus P.
dc.contributor.author Lupindu, Athumani M.
dc.contributor.author Damborg, Peter
dc.contributor.author Rosenkrantz, Jesper T.
dc.contributor.author Minga, Uswege M.
dc.contributor.author Mtambo, Madundo M. A.
dc.contributor.author Olsen, John E.
dc.date.accessioned 2018-06-13T11:29:06Z
dc.date.available 2018-06-13T11:29:06Z
dc.date.issued 2018-04-01
dc.identifier.other https://doi.org/10.1089/mdr.2016.0297
dc.identifier.uri http://www.suaire.suanet.ac.tz:8080/xmlui/handle/123456789/2333
dc.description Journal article en_US
dc.description.abstract This study provides an estimate of antimicrobial resistance in intestinal indicator bacteria from humans (n = 97) and food animals (n = 388) in Tanzania. More than 70% of all fecal samples contained tetracycline (TE), sulfamethoxazole (STX), and ampicillin (AMP)-resistant coliforms, while cefotaxime (CTX)-resistant coliforms were observed in 40% of all samples. The average Log10 colony forming units/g of CTX-resistant coliforms in samples from humans were 2.20. Of 390 Escherichia coli tested, 66.4% were resistant to TE, 54.9% to STX, 54.9% to streptomycin, and 36.4% to CTX. Isolates were commonly (65.1%) multiresistant. All CTX-resistant isolates contained blaCTX-M gene type. AMP- and vancomycin-resistant enterococci were rare, and the average concentrations in positive samples were low (log10 0.9 and 0.4, respectively). A low-tomoderate resistance (2.1–15%) was detected in 240 enterococci isolates to the drugs tested, except for rifampicin resistance (75.2% of isolates). The average number of sulII gene copies varied between Log10 5.37 and 5.68 with no significant difference between sample source, while cattle had significantly higher number of tetW genes than humans. These findings, based on randomly obtained samples, will be instrumental in designing antimicrobial resistance (AMR) intervention strategies for Tanzania. en_US
dc.language.iso en en_US
dc.publisher Mary Ann Liebert, Inc. en_US
dc.subject fecal indicator bacteria, antimicrobial resistance, blactx-M, Tanzania en_US
dc.title First Report on a Randomized Investigation of Antimicrobial Resistance in Fecal Indicator Bacteria from Livestock, Poultry, and Humans in Tanzania en_US
dc.type Article en_US
dc.url https://doi.org/10.1089/mdr.2016.0297 en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search SUA IR


Advanced Search

Browse

My Account

Statistics