Identification of felis catus gammaherpesvirus 1 in Tsushima leopard cats (prionailurus bengalensis euptilurus) on Tsushima island, Japan

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dc.contributor.authorMakundi, Isaac
dc.contributor.authorKoshida, Yushi
dc.contributor.authorEndo, Yasuyuki
dc.contributor.authorNishigaki, Kazuo
dc.date.accessioned2022-10-25T10:25:55Z
dc.date.available2022-10-25T10:25:55Z
dc.date.issued2018-07-19
dc.descriptionJournal Articleen_US
dc.description.abstractFelis catus gammaherpesvirus 1 (FcaGHV1) is a widely endemic infection of domestic cats. Current epidemiological data identify domestic cats as the sole natural host for FcaGHV1. The Tsushima leopard cat (TLC; Prionailurus bengalensis euptilurus) is a critically endangered species that lives only on Tsushima Island, Nagasaki, Japan. Nested PCR was used to test the blood or spleen of 89 TLCs for FcaGHV1 DNA; three (3.37%; 95% CI, 0.70–9.54) were positive. For TLC management purposes, we also screened domestic cats and the virus was detected in 13.02% (95% CI, 8.83–18.27) of 215 cats. Regarding phylogeny, the partial sequences of FcaGHV1 from domestic cats and TLCs formed one cluster, indicating that similar strains circulate in both populations. In domestic cats, we found no significant difference in FcaGHV1 detection in feline immunodeficiency virus-infected (p = 0.080) or feline leukemia virus-infected (p = 0.163) cats, but males were significantly more likely to be FcaGHV1 positive (odds ratio, 5.86; 95% CI, 2.27–15.14) than females. The higher frequency of FcaGHV1 detection in domestic cats than TLCs, and the location of the viral DNA sequences from both cats within the same genetic cluster suggests that virus transmission from domestic cats to TLCs is likely.en_US
dc.description.sponsorshipJapan Society for the Promotion of Science KAKENHI (grant number 15H04602).en_US
dc.identifier.citationdoi:10.3390/v10070378en_US
dc.identifier.urihttp://www.suaire.sua.ac.tz/handle/123456789/4723
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofseriesViruses;10. 378
dc.subjectGammaherpesvirusen_US
dc.subjectFelineen_US
dc.subjectDomestic caten_US
dc.subjectTsushima leopard caten_US
dc.subjectTsushima islanden_US
dc.subjectFcaGHV1en_US
dc.subjectMolecular epidemiologyen_US
dc.titleIdentification of felis catus gammaherpesvirus 1 in Tsushima leopard cats (prionailurus bengalensis euptilurus) on Tsushima island, Japanen_US
dc.typeArticleen_US
dc.urlViruses 2018, 10, 378; doi:10.3390/v10070378en_US

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