Seroprevalence and associated risk factors of chikungunya, dengue, and zika in eight districts in Tanzania

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dc.contributor.authorMwanyika, Gaspary O.
dc.contributor.authorSindato, Calvin
dc.contributor.authorRugarabamu, Sima
dc.contributor.authorRumisha, Susan F.
dc.contributor.authorKarimuribo, Esron D.
dc.contributor.authorMisinzo, Gerald
dc.contributor.authorRweyemamu, Mark M.
dc.contributor.authorHamid, Muzamil M. Abdel
dc.contributor.authorHaider, Najmul
dc.contributor.authorVairo, Francesco
dc.contributor.authorKock, Richard
dc.contributor.authorMboera, Leonard E.G.
dc.date.accessioned2022-09-06T09:54:23Z
dc.date.available2022-09-06T09:54:23Z
dc.date.issued2021
dc.descriptionInternational Journal of Infectious Diseases 111 (2021) pp. 271–280en_US
dc.description.abstractBackground: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses in Tanzania. Methods: The study covered the districts of Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa, Kyela, Mvomero, and Ukerewe in Tanzania. Blood samples were collected from individuals recruited from house- holds and healthcare facilities. An ELISA was used to screen for immunoglobulin G antibodies against CHIKV, DENV, and ZIKV. Results: A total of 1818 participants (median age 34 years) were recruited. The overall CHIKV, DENV, and ZIKV seroprevalence rates were 28.0%, 16.1%, and 6.8%, respectively. CHIKV prevalence was highest in Buhigwe (46.8%), DENV in Kinondoni (43.8%), and ZIKV in Ukerewe (10.6%) and Mvomero (10.6%). Increas- ing age and frequent mosquito bites were significantly associated with CHIKV and DENV seropositivity ( P < 0.05). Having piped water or the presence of stagnant water around the home ( P < 0.01) were as- sociated with higher odds of DENV seropositivity. Fever was significantly associated with increased odds of CHIKV seropositivity ( P < 0.001). Visiting mines had higher odds of ZIKV seropositivity ( P < 0.05). Conclusions: These findings indicate that DENV, CHIKV, and ZIKV are circulating in diverse ecological zones of Tanzania. There is a need to strengthen the control of mosquito-borne viral diseases in Tanzania.en_US
dc.identifier.urihttp://www.suaire.sua.ac.tz/handle/123456789/4523
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.subjectChikungunyaen_US
dc.subjectDengue Zikaen_US
dc.subjectSeroprevalenceen_US
dc.subjectRisk factorsen_US
dc.subjectTanzaniaen_US
dc.titleSeroprevalence and associated risk factors of chikungunya, dengue, and zika in eight districts in Tanzaniaen_US
dc.typeArticleen_US
dc.urlhttps://doi.org/10.1016/j.ijid.2021.08.040en_US

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