Mycobacterial adenitis: role of mycobacterium bovis, non-tuberculous mycobacteria, hiv infection, and risk factors in arusha, Tanzania
| dc.contributor.author | Mfinanga, S .G .M. | |
| dc.contributor.author | Morkve, O. | |
| dc.contributor.author | Kazwala, R. R. | |
| dc.contributor.author | Cleaveland, S. | |
| dc.contributor.author | Sharp, M. J. | |
| dc.contributor.author | Kunda, J. | |
| dc.contributor.author | Nilsen, R. | |
| dc.date.accessioned | 2017-06-24T07:23:18Z | |
| dc.date.available | 2017-06-24T07:23:18Z | |
| dc.date.issued | 2004-04 | |
| dc.description | East African Medical Journal 2004, Vol. 81 (4) | en_US |
| dc.description.abstract | Objective: To assess risk factors and mycobacterial agents in mycobacterial adenitis. Design: Cross sectional involving comparison analysis of high-risk groups. Setting: Seven hospitals in rural and semi-rural districts of Arusha. Subjects: The study comprised of 457 patients of clinically diagnosed mycobacterial adenitis. Interventions: Biopsy materials were cultured and identification of mycobacterial isolates, and HIV infection testing were performed using standard methods. A questionnaire was used to establish information for assessing risk factors. Main outcome measures: Proportions of mycobacterial isolates, risk factors and odds ratios. Results: Of the 457 specimens, 65(14.2%) were culture positive. Isolates identified were M. bovis, 7(10.8%) M. tuberculosis, 27(41.5%) and non-tuberculous mycobacteria 31(47.7%). HIV infection and ingestion of raw milk were linked with increased risk of M. bovis infection by OR of 13.6 (95% CI, 1.7 - 109.9) and 15.28 (3.26 - 71.7), respectively. On multivariate analysis, an OR of 16.2 (1.3 - 201.3) for having M. bovis adenitis was linked to HIV infection, raw milk and houses with poor ventilation. An OR of 5.2 (1.2 - 20.6) for non-tuberculous mycobacterial adenitis was linked to history of TB in the family, HIV infection, raw milk, raw animal products and poor knowledge on transmission of tuberculosis. Conclusions: M. bovis caused one out of ten cases of culture positive mycobacterial adenitis. Non-tuberculous mycobacteria were more common than M. tuberculosis (50% and 40% of the cases, respectively). HIV infection and raw animal products are among the risk factors identified for M. bovis and non-tuberculous mycobacterial adenitis. | en_US |
| dc.identifier.issn | 0012-835X | |
| dc.identifier.uri | https://www.suaire.sua.ac.tz/handle/123456789/1696 | |
| dc.language.iso | en | en_US |
| dc.publisher | East African Medical Journal | en_US |
| dc.subject | Mycobacterial adenitis | en_US |
| dc.subject | Mycobacterium bovis | en_US |
| dc.subject | Non-tuberculous | en_US |
| dc.subject | Tuberculosis (TB) | en_US |
| dc.subject | Mycobacterial agents | en_US |
| dc.subject | HIV infection testing | en_US |
| dc.title | Mycobacterial adenitis: role of mycobacterium bovis, non-tuberculous mycobacteria, hiv infection, and risk factors in arusha, Tanzania | en_US |
| dc.type | Article | en_US |
| dc.url | https://www.ajol.info/index.php/eamj/article/view/9150/2072 | en_US |