Assessment of antimicrobial activity of velvet bush willow (Combretum molle) crude bark extracts on selected bacteria species

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dc.contributor.authorMgonja, Frida Richard
dc.contributor.authorAlly, Mohamed Hamed Sango
dc.date.accessioned2022-03-22T11:36:25Z
dc.date.available2022-03-22T11:36:25Z
dc.date.issued2021-10
dc.description.abstractTreatment and control of infectious diseases in humans and animals play a vital role in prevention of illness and death. Conventional drugs treatment has been providing effective therapy for treatment of infections caused by pathogenic microorganisms; However, some do not respond to conventional therapy. Conventional therapy are expensive and have more adverse side effects. Plant based medicinal productshas been used as an alternative curative for infections caused by resistant pathogenic microorganisms, moreover, plant medicinal products have less adverse side effects. This study was conducted to assess thecrude Combretummolle bark extracts antimicrobial activityagainst three selected bacteria species. Three solvents, distilled water; ethanol and acetone were used for crude combretum molle bark extraction. The agar well diffusion method was used to assess antimicrobial activity against Streptococcus pyogenes, Pseudomonas aeruginosa and Escherichia coli. A minimum inhibition concentration (MIC) of the most active extracts was determined by the broth dilution technique. Extracts from three solvents tested demonstrated antimicrobial activity with zone of inhibition diameters ranging from 14 to 24 mm. Acetone extract was the most potent with its minimum inhibitory concentration (MIC) ranging from 1.25 to 2.50 mg/ml. There was no statistically significant difference (P>0.05) in the potency of the three extracts and standard antibiotic ciprofloxacin on the bacteria species tested. The study showed that the crude bark extract of C. molle has antimicrobial activity against all the test microorganisms.en_US
dc.identifier.issn2575-5889
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/3989
dc.language.isoenen_US
dc.subjectCombretum Molle Crude Bark Extracten_US
dc.subjectStreptococcus Pyogenesen_US
dc.subjectPseudomonas Aeruginosa Escherichia Colen_US
dc.subjectAntimicrobial Activityen_US
dc.titleAssessment of antimicrobial activity of velvet bush willow (Combretum molle) crude bark extracts on selected bacteria speciesen_US
dc.typeArticleen_US
dc.urlhttp://www.sciencepublishinggroup.com/j/ijbbmben_US

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