Profile of plasma lipids and degree of derangements among the elderly of Morogoro region, Tanzania
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Tanzania Journal of Health Research
Abstract
Changes in lifestyles and ageing have been associated with growing rates of modifiable
cardiovascular risk factors (CRF). Dyslipidemia is one of the CRF associated with numbers of cardiovascular
diseases. This descriptive cross-sectional study was conducted to determine the profile and degree of
derangements of plasma lipids among 300 (176 females and 124 males) elderly individuals aged ≥60 years in
Morogoro, Tanzania. The calorimetric enzymatic methods and the Friedewal’s equation were used for
determination of cholesterols and triglycerides (TG). Social and demographic characteristics were gathered by
structured questionnaires. The logistic regression models were used to identify the determinants of abnormal
serum lipids level. Mean Total Cholesterols (TC) and Low Density Lipoprotein Cholesterols (LDL-C) in females
exceeded significantly that of males. Mean TC, LDL-C as well as TG (mg/dL) declined significantly with age while
mean High Density Lipoprotein Cholesterols (HDL-C) also declined but only slightly. Elderly females were two
times more likely to have elevated TC (OR=2.11; 95% CI: 1.04-4.28: P=0.05) and LDL-C (OR=2.15; 95% CI: 1.17-3.97:
P=0.019) and three times to have lowered HDL-C (OR=3; 95% CI: 1.97-5.30: P<0.001) than males. Urban residents
were about two times more likely to have elevated LDL-C (OR=1.84; 95% CI: 1.04-3.25: P=0.047) than their rural
counterparts. Body Mass Index of ≥30 kg/m 2 was also associated with elevated LDL-C (OR=1.89; 95% CI: 1.05-
3.42: P=0.045) and lowered HDL-C (OR=2.18; 95% CI: 1.3-3.65: P=0.004), respectively. The present study has
established the profile and level of derangements of serum lipids among the elderly of Morogoro region in
Tanzania. It appears that, female sex and BMI of ≥ 30kg/ m 2 are significant factors for elevated TC, LDL-C and
lowered HDL-C while urban life is a significant factor for elevated LDL-C.
Description
Tanzania Journal of Health Research, Volume 16, Number 4, October 2014
Keywords
Plasma lipids, Dyslipidemia, Cardiovascular diseases, Elderly, Lifestyle, Tanzania