Human and animal thermophilic Campylobacter infections in East African countries: Epidemiology and antibiogram
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Date
2017
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Biomedical Journal of Scientific and Technical research
Abstract
Purpose: Campylobacter mediated diarrhoea is a leading cause of gastroenteritis worldwide. The organisms colonize the gastrointestinal
tract of different animal species without causing disease symptoms. Humans acquire infections through contact with or consumption of
contaminated meat especially raw/undercooked poultry meat. The rapid emergence of antibiotic-resistant Campylobacter strains heightens
the public health concern of the organisms. The aim of this review was to summarise information on the epidemiology and antibiogram of
Campylobacter in humans and animals in East African countries.
Method: A structured literature search of PUBMED and Science Direct electronic databases.
Results: Forty reports on thermophilic Campylobacter were identified in four of the five East African countries in the following order;
Kenya (16), Tanzania (17), Uganda (4) and Rwanda (3). No study was found to report thermophilic Campylobacter infections in either
humans or animals in Burundi. Studies on animals reported colonization of both domestic and wild species. Of the studies that described
Campylobacter infections in humans, both symptomatic and asymptomatic subjects were reported to be infected; with higher prevalence in
subjects younger than five years old. Among isolates, some demonstrated antimicrobial resistance.
Conclusion: Available information for both human and animal Campylobacteriosis in the region is however sparse thus calling for more
research to better understand the epidemiology of infections caused by the organism including clonal dependence and independence of
human and animal derived isolates. This understanding will help researchers and health program developers in designing and implementing
effective control strategies. Since the organism is zoonotic its control strategies should adopt the “One Health” approach involving
collaborative efforts from veterinary and human medicine.
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Keywords
Adults; Children; Campylobacter; Chickens; Diarrhoea; Food animals; Wild animals