Sokoine University of Agriculture

Surgical sterilization of the African Giant Pouched Rats

Show simple item record Werema, C. W. Samson, R. Ndossi, D. G. Kashoma, I. P. Mwakijungu, E. 2018-06-20T15:39:41Z 2018-06-20T15:39:41Z 2015-08-25
dc.identifier.issn 0856 - 1451
dc.description.abstract Surgical sterilization of rodents is increasing as a result of increased biomedical research centers which employ rodents. In order for them to perform their duties effectively, the rodents have to be sterile to avoid interference from estrus, pregnancy and lactation. Other reasons include control of breeding, treatment of diseases or conditions such as tumors cysts, pyometra, pyometritis, and endometritis. In this study three surgical procedures were performed to African Giant Pouched Rats; 6 females were ovariectomized, 6 females were ovariohysterectomized, and 6 males were Orchidectomized. All eighteen (18) animals in the study recovered well and have returned to APOPO to continue with the training on smelling and detecting landmines and tuberculosis in human sputum samples without any difficulties. Complications from these surgical procedures are rare but comprise anesthetic overdose, dehydration, hypothermia, pulmonary hypostatic congestion, hemorrhage, eviscerations, wound dehiscence, and infections. However, many of these complications can be prevented by careful physical examination and selection of health animals fit for the intended surgical procedure, as well as adherence to all principles of surgery. This study has demonstrated the three surgical procedures for African Giant pouched rats as being useful to veterinarians in public/private practice and/or in biomedical research facilities. en_US
dc.language.iso en en_US
dc.publisher Tanzania Veterinary Journal en_US
dc.relation.ispartofseries 30 (2): 85 - 93;
dc.subject Surgical sterilization en_US
dc.subject Ovariectomy en_US
dc.subject Ovariohysterectomy en_US
dc.subject Orchidectomy en_US
dc.subject African giant pouched rats en_US
dc.title Surgical sterilization of the African Giant Pouched Rats en_US
dc.type Article en_US

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