Sokoine University of Agriculture

Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings

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dc.contributor.author Mahoney, A.M
dc.contributor.author Weetjens, B.J
dc.contributor.author Cox, C
dc.contributor.author Beyene, N
dc.contributor.author Mgode, G
dc.contributor.author Jubitana, M
dc.contributor.author Kuiper, D
dc.contributor.author Kazwala, R
dc.contributor.author Mfinanga, G.S
dc.contributor.author Durgin, A
dc.contributor.author Poling, A
dc.date.accessioned 2017-04-04T12:17:17Z
dc.date.available 2017-04-04T12:17:17Z
dc.date.issued 2011-07-17
dc.identifier.issn 1937- 8688
dc.identifier.uri http://www.suaire.sua.ac.tz/handle/123456789/1378
dc.description Pan African Medical Journal 2011, Vol 9:28 en_US
dc.description.abstract Giant African pouched rats previously have detected tuberculosis (TB) in human sputum samples in which the presence of TB was not initially detected by smear microscopy. Operant conditioning principles were used to train these rats to indicate TB-positive samples. In 2010, rats trained in this way evaluated 26,665 sputum samples from 12,329 patients. Microscopy performed at DOTS centers found 1,671 (13.6%) of these patients to be TB-positive. Detection rats identified 716 additional TB-positive patients, a 42.8% increase in new-case detection. These previously unreported data, which extend to over 20,000 the number of patients evaluated by pouched rats in simulated second-line screening, suggest that the rats can be highly valuable in that capacity. en_US
dc.language.iso en en_US
dc.subject Giant African pouched en_US
dc.subject Tuberculosis en_US
dc.subject Human sputum en_US
dc.subject TB en_US
dc.title Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings en_US
dc.type Article en_US


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